For many women, particularly those who are older than 40 or who have gone through menopause, physical desire isn't the primary motivation for sex. If a particular medication is affecting your comfort with sex or desire for sex, your doctor may be able to suggest an alternative. Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Mayo Clinic does not endorse companies or products. If you take medications and are concerned about your level of desire, review your medications with your doctor. What it means to be sexually satisfied differs for everyone. Show references Frequently asked questions. Whatever the cause, differences in sexual desire between partners can sometimes lead to feelings of isolation, frustration, rejection or resentment.
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